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PGT-P can test for polygenic conditions in embryos

For hopeful parents living with genetic conditions, preimplantation genetic testing offers the hope of having healthy children. PGT-P is a type of genetic testing of embryos that can identify polygenic conditions, so that only embryos free of those conditions are made available for transfer. By combining IVF and genetic testing, parents can break the chain of inherited genetic conditions in their families.

PGT-P creates an “embryo health score” for each embryo created through IVF. The test produces a report that clarifies the risk of each embryo being affected by specific genetic diseases or disorders, such as heart disease, cancer and diabetes. When you come to us for IVF in San Antonio and choose genetic testing, the test will be performed on sample cells taken from each embryo. The biopsy process doesn’t damage the embryo’s future potential to develop into a fetus, and all embryos are frozen and safely stored while you await the results.

What are polygenic disorders?

Polygenic disorders can happen when there is a mutation in more than one gene. Often, environmental factors play a role in whether or not an individual is affected by these mutations. Polygenic disorders may or may not have a significant impact on a person’s life and health. Here are several of the most common.

  • Asthma
  • Attention deficit hyperactivity disorder (ADHD)
  • Autism
  • Bipolar disorder
  • Cancer
  • Cleft palate
  • Congenital heart defects
  • Congenital hip dysplasia
  • Dementia
  • Diabetes
  • Heart disease
  • Major depressive disorder
  • Neural tube defects
  • Obesity
  • Pyloric stenosis
  • Schizophrenia

PGT-P is combined with PGT-A to provide extensive information to support the selection of the best embryo for transfer, so you can also learn the sex of each embryo if you choose.

Who needs PGT-P?

If you are including PGT-A as part of your IVF cycle, PGT-P is an additional test that can provide a great deal of information using the same sample cells. It is ideal for people who have a personal or family history of a polygenic condition and hope to avoid passing that condition on to their future children.

If you are interested in finding out more about available genetic tests and whether they can benefit you in your family planning – especially if you are considering IVF in San Antonio – contact us to schedule a consultation with an experienced reproductive endocrinologist. We can explain your options and help you decide if PGT-P is a wise choice for you.